Biography
Director, Natural Health and Food Products Research Group (NRG)
Canada Research Chair in Phytoanalytics
Dr. Paula Brown is the Director of the BC Institute of Technology's Natural Health and Food Products Research Group (NRG), which has been actively supporting the NHP industry for over a decade through applied research activities, including product development, establishment of quality standards and regulatory compliance. By providing fundamental investigations on product quality, safety and efficacy, BCIT supports industry through the entire continuum, from grower to manufacturer, ensuring product integrity is maintained. Dr. Brown has spoken at numerous conferences over the last decade on product quality standards, analytical method validation and is currently the "Quality Focus" columnist for Nutraceuticals World.
An active volunteer, Dr. Brown sits on various Boards, Committees and Working Groups including the Dietary Supplement Joint Committee (NSF) and the Analytical Laboratories and Botanical Raw Material Committees (American Herbal Products Association). She is currently a Director for the Investment Agriculture Foundation of BC which strategically invests federal and provincial funds in support of innovative projects to benefit the agri-food industry. In 2003 she was a founding Director of the NHP Research Society of Canada, dedicated to supporting and promoting scientifically rigorous NHP research and education and most recently she joined the Advisory Board of the American Botanical Council.
Dr. Brown serves on two grant review committees for National Center for Complementary & Alternative Medicine, NIH and is a reviewer for numerous peer-reviewed Journals in the field of analytical chemistry and natural products. A Fellow of the AOAC International (2009), she served as Referee for the Dietary Supplement Methods Committee from 2004-2009, is a current member of the Dietary Supplement Task Force (2003-present), and has participated on seven Expert Review Panels for AOAC. In addition she has directed three full collaborative studies; Goldenseal (Official Methods SM 2008.04), Ginseng (SM 2008.05) and Echinacea (in review).
Dr. Brown is currently a member of the Natural Health Products Program Advisory Committee (PAC), and Chair of it's Product Testing Working Group, convened to make recommendations on policy related to standards of evidence for quality. The mandate of the PAC is to provide the NHP Program Directorates (Natural Health Products Directorate, Marketed Health Products Directorate and Health Products and Food Branch Inspectorate) with advice and recommendations on current and emerging issues relevant to the Canadian regulatory framework for natural health products.
Recent Citations for Paula Brown
- Comparisons of large (Vaccinium macrocarpon ait.) and small (Vaccinium oxycoccos L., Vaccinium vitis-idaea L.) cranberry in British Columbia by phytochemical determination, antioxidant potential, and metabolomic profiling with chemometric analysis
- Lycopene differentially induces quiescence and apoptosis in androgen-responsive and -independent prostate cancer cell lines
- Determination of mitragynine in mitragyna speciosa raw materials and finished products by liquid chromatography with UV detection: single-laboratory validation
- Proteomic analysis of the effects of aged garlic extract and its FruArg component on lipopolysaccharide-induced neuroinflammatory response in microglial cells
- Optimization and single-laboratory validation of a method for the determination of flavonolignans in milk thistle seeds by high-performance liquid chromatography with ultraviolet detection
- Quantification of pyrrolizidine alkaloids in North American plants and honey by LC-MS: single laboratory validation
- Curcuminoids in turmeric roots and supplements: method optimization and validation
- Determination of β-N-methylamino-L-alanine, N-(2-aminoethyl)glycine, and 2,4-diaminobutyric acid in food products containing cyanobacteria by ultra-performance liquid chromatography and tandem mass spectrometry: single-laboratory validation
- Variation of select flavonols and chlorogenic acid content of elderberry collected throughout the Eastern United States
- AOAC SMPR® 2016.016: standard method performance requirements (SMPRs) for identification of non-animal-derived proteins in dietary supplements
- AOAC SMPR® 2016.013
- AOAC SMPR® 2016.014
- AOAC SMPR® 2016.015: standard method performance requirements (SMPRs) for identification of animal-derived proteins in dietary supplements
- Determination of ginsenoside content in Asian and North American ginseng raw materials and finished products by high-performance liquid chromatography: single-laboratory validation
- Determination of ginsenoside content in Panax ginseng C.A. Meyer and Panax quinquefolius L. root materials and finished products by high-performance liquid chromatography with ultraviolet absorbance detection: interlaboratory study
- How to qualify an analytical laboratory for analysis of herbal dietary ingredients and avoid using a "dry lab": a review of issues related to using a contract analytical laboratory by industry, academia, and regulatory agencies
- Accuracy, precision, and reliability of chemical measurements in natural products research
- Single-laboratory validation of a method for the detection and/or quantification of select alkaloids in goldenseal supplements and raw materials by reversed-phase high-performance liquid chromatography
- Determination of hydrastine and berberine in goldenseal raw materials, extracts, and dietary supplements by high-performance liquid chromatography with UV: collaborative study
- AOAC SMPR® 2016.003: standard method performance requirements for quantitation of curcuminoids
- Determination of major phenolic compounds in Echinacea spp. raw materials and finished products by high-performance liquid chromatography with ultraviolet detection: single-laboratory validation matrix extension
- Current initiatives for the validation of analytical methods for botanicals
- Determination of Aloin A and Aloin B in aloe vera raw materials and finished products by high-performance liquid chromatography: single-laboratory validation
- Determination of phenolic constituents in echinacea raw materials and dietary supplements by HPLC-UV: collaborative study
- The importance of method selection in determining product integrity for nutrition research
- Determination of anthocyanins in cranberry fruit and cranberry fruit products by high-performance liquid chromatography with ultraviolet detection: single-laboratory validation
- A review of the chemistry of the genus Crataegus
- Synthesis of galactofuranosyl-containing oligosaccharides corresponding to the glycosylinositolphospholipid of Trypanosomacruzi
- Evaluation of the antiproliferative effects of Essiac on in vitro and in vivo models of prostate cancer compared to paclitaxel
Subscribe to Paula Brown RSS feed