BCIT Citations Collection | BCIT Institutional Repository

BCIT Citations Collection

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Collection of published works from BCIT researchers, faculty, and instructors.

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Gene expression noise in spatial patterning
Positional information in developing embryos is specified by spatial gradients of transcriptional regulators. One of the classic systems for studying this is the activation of the hunchback (hb) gene in early fruit fly (Drosophila) segmentation by the maternally-derived gradient of the Bicoid (Bcd) protein. Gene regulation is subject to intrinsic noise which can produce variable expression. This variability must be constrained in the highly reproducible and coordinated events of development. We identify means by which noise is controlled during gene expression by characterizing the dependence of hb mRNA and protein output noise on hb promoter structure and transcriptional dynamics. We use a stochastic model of the hb promoter in which the number and strength of Bcd and Hb (self-regulatory) binding sites can be varied. Model parameters are fit to data from WT embryos, the self-regulation mutant hb(14F), and lacZ reporter constructs using different portions of the hb promoter. We have corroborated model noise predictions experimentally. The results indicate that WT (self-regulatory) Hb output noise is predominantly dependent on the transcription and translation dynamics of its own expression, rather than on Bcd fluctuations. The constructs and mutant, which lack self-regulation, indicate that the multiple Bcd binding sites in the hb promoter (and their strengths) also play a role in buffering noise. The model is robust to the variation in Bcd binding site number across a number of fly species. This study identifies particular ways in which promoter structure and regulatory dynamics reduce hb output noise. Insofar as many of these are common features of genes (e.g. multiple regulatory sites, cooperativity, self-feedback), the current results contribute to the general understanding of the reproducibility and determinacy of spatial patterning in early development., Peer-reviewed article, Publisher. Received July 4, 2010; Accepted December 28, 2010; Published February 3, 2011.
Getting serious about sustainability
One-planet living represents the per capita share of global ecosystem services that each person on Earth could use were humanity to live equitably within ecological carrying capacity. My research uses ecological footprint analysis to explore the potential for the City of Vancouver to achieve one-planet living. Specifically, I examine what reductions in per capita ecological footprint would be necessary, what policies or changes to management practices are available to the City to facilitate those reductions, and what one-planet living might “look like” if those policies and changes to urban management practices were implemented. I use 2006 data to conduct an integrated urban metabolism and ecological footprint assessment for the City in order to establish a baseline from which to estimate the necessary reductions in material and energy consumption. I develop lifestyle archetypes of societies living at a one-planet ecological footprint (both real and hypothetical) to inform estimates on how changes in diet, buildings, consumables and waste, transportation and water could achieve one-planet living in Vancouver. I also draw on examples from the international sustainable cities literature and interviews with City of Vancouver and Metro Vancouver staff and elected representatives to develop policy proposals for reducing Vancouver’s ecological footprint. Getting to one-planet living in Vancouver requires at least a 58% reduction in the per capita ecological footprint with the greatest contributions coming from reducing food waste, red meat consumption, and virtually eliminating personal motor vehicle use (shifting instead to an 86% walk, cycle and transit mode share which the City already achieves in its Downtown). The City has and can continue to influence individual and corporate choices through zoning and permitting. However, citizens would have to accept lifestyle changes pertaining to food and personal consumption to achieve the one-planet living goal. Involvement by senior governments in reducing the ecological footprint is also required. It remains to be seen whether Vancouverites, or any population accustomed to modern consumer lifestyles, will voluntarily accept and implement the changes necessary to achieve equitable sustainability as articulated by one-planet living., Thesis, Published.
A greenhouse gas emissions inventory and ecological footprint analysis of Metro Vancouver residents’ air travel
Ecological Footprint Analysis (EFA) at the city or regional scale does not typically include air travel due to a lack of readily available data. However, knowing the “load” placed on nature by various lifestyle choices, including air travel, is essential if we hope to enable society to live sustainably within ecological limits. This paper provides methods for including air travel in urban EFA, in a manner that is accessible to those that are interested in the complexities of urban sustainability. Our goal is to use the case of the Vancouver Metropolitan region to illustrate two methods in such a way that they can be replicated or adapted for use in other cities and regions. We found that the greenhouse gas emissions of air travel by Metro Vancouver residents for 2006 is between 1,191,070 and 1,402,420 tonnes of carbon dioxide equivalent (tCO2e). The resulting ecological footprint is between 287,030 and 337,980 global hectares (gha), or between 0.136 and 0.160 gha/capita. The dedicated carbon sink required to neutralize the carbon dioxide emissions from Metro Vancouver residents’ air travel alone is equivalent to twice the land area of the region (283,183 hectares)., Peer-reviewed article, Published. Received: July 15, 2013 ; Accepted: September 16, 2013 ; Online Published: September 27, 2013.
Heat, air and moisture transport properties of several North American bricks and mortar mixes
Hygrothermal models are emerging as practical building design tools. These models require a set of reliable inputs to provide results that are meaningful to the designers. One of these inputs is the set of heat, air and moisture transport properties of materials. For any given class of building materials the properties may vary within a broad range. This paper reports the porosity, density, matrix density, thermal conductivity, equilibrium moisture content, water vapor permeability, water absorption coefficient, liquid diffusivity and air permeability of six types of bricks and four mortar mixes that are commonly used in North America. The experimental and analytical procedures follow either international standards or well-established methodologies., Peer reviewed article, Published. Received 9 July 2003; accepted 17 March 2004.
Heat, air and moisture transport properties of three North American stuccos
Heat, air, and moisture transfer models that are used as practical building design tools require reliable inputs to provide meaningful results. One of these inputs is the set of heat, air, and moisture transport properties of materials. For any given class of building materials the properties may vary within a broad range. This paper reports the porosity, density, matrix density, thermal conductivity, equilibrium moisture content, water vapor permeability, water absorption coefficient, liquid diffusivity, and air permeability of regular lime stucco, regular Portland cement stucco, and acrylic stucco that are commonly used in North America. The experimental and analytical procedures follow either international standards or well-established methodologies., Peer reviewed article, Published. Received 9 January 2004; accepted 13 October 2005; published online 25 January 2006.
Hedging the risk of increased emissions in long term energy planning
The feasibility of meeting emission targets is often evaluated using long range planning optimization models in which the targets are incorporated into the system constraints. These models typically provide one ‘optimal’ solution that considers only a deterministic representative value of emissions for each technology and do not consider the risk of exceeding expected emissions for a given optimal solution. Since actual emissions for any given technology are uncertain, implementation of such an optimal solution carries inherent risk that emissions will exceed the given target. In this paper, we implement a stochastic risk structure into the OSeMOSYS optimization model to incorporate uncertainty related to the emissions of electricity generation technologies. For a given risk premium, defined as the additional amount that society is willing to pay to reduce the risk of exceeding the cost optimal system emissions, we determine the generation technology mix that has the lowest risk of exceeding this baseline. We focus on emissions risk since the literature on emissions risk is sparse while the literature on other risks such as policy risks, financial risks and technological risks is extensive. We apply the model to a case study of a primarily fossil based jurisdiction and find that, when risk is incorporated, solar and wind technologies are built out seven and five years earlier respectively and that carbon free technologies such as coal with carbon capture and storage (CCS) become effective alternatives in the energy mix when compared to the ‘optimal’ solution without consideration of risk, though this does not include the risk of carbon leakage from CCS technologies. If nuclear is included as a generation option, we find that nuclear provides an effective risk hedge against exceeding emissions., Peer-Reviewed Article, Final article published. Available online 12 February 2017., Peer reviewed
Hygrothermal modeling of aerated concrete wall and comparison with field experiment
Proceedings of 3rd International Building Physics Conference: 27 August 2006, Montreal, QC. A two-dimensional heat, air and moisture transport model called hygIRC is adapted to simulate a well-documented field exposure of an aerated concrete wall section. Difficulties are encountered due to a few missing information on boundary conditions of the exposure and hygrothermal properties of aerated con-crete. The paper presents how these inadequacies were overcome to simulate the hygrothermal behavior of the wall section. Appropriate assumptions were made due to justifiable reasons. Then the model provides temporal and spatial distributions of temperature and relative humidity for an extended period that are in ex-cellent agreement with the documented field data. The paper presents the justifications for the assumptions and the comparison of experimental and simulation results., Conference paper, Published. A version of this document is published in: 3rd International Building Physics Conference, Montreal, QC., August 27, 2006, pp. 321-328.
Hygrothermal performance assessment of vented and ventilated wall systems
Proceedings of Thermal Performance of the Exterior Envelopes of Whole Buildings XII International Conference, At Clearwater Beach, Florida, USA, December 2013. Based on analysis of the drying and wetting potentials of a particular local climate, designers choose wall systems with or without an air gap between a sheathing membrane and a cladding layer. In addition to the capillary break that the air gap provides, thereby reducing the moisture transfer from wet cladding to the interior of the wall, the airspace will add the thermal resistance of the wall system and reduce the heat flow across the wall system. These moisture and thermal performances are straightforward to understand if the air in the air cavity is assumed to be a “still air.” In this paper, an experimental study is undertaken to under-stand the impact of airflow through an air cavity on the moisture and thermal performance of wall systems. To achieve this objective three test panels are instrumented and monitored in the field-experimental setting: one with no air gap, another one with an air gap but restricted airflow, and the third one with an air gap and open for airflow. The second and third wall systems have the same air gap width but different top flashing designs creating vented and ventilated wall systems. For the wall systems’ orientation and boundary conditions considered in this study, the wall with no air gap accumulates relatively high moisture content on the sheathing board, stud, and bottom plate and also has high moisture content changes in a year cycle when compared to the vented and ventilated wall systems. In general, the hygrothermal performances of vented and ventilated wall systems are comparable. During the winter period when relatively high moisture accumulation occurs, the upper section of the ventilated wall system shows slightly lower moisture content compared to that of the vented wall system. The temperature readings of the sheathing boards in the vented and ventilated wall systems are slightly warmer than that of the wall with no air gap for 85.5% and 73% of the time (based on hourly data of a year), respectively. For the balance of a period of time, the sheathing boards in the walls with an air cavity are slightly cooler than that of the wall with an air gap. Although the low temperature on the sheathing board, which is caused by solar radiation-induced airflow, is beneficial during a cooling season, the air gap and the associated airflow may reduce the heat gain that may be obtained from solar radiation during the heating season. The implications of air cavity and flashing design (airflow rate) on the heating and cooling load calculations of different orientations, wall configurations, and climate require further investigation., Conference paper, Published.
Hygrothermal performance of exterior wall systems using an innovative vapour retarder in Canadian climate
Proceeding of the 4th International Building Physics Conference: 15 June 2009, Istanbul, Turkey. This paper provides highlights of the research work carried out at the National Research Council Canada, Institute for Research in Construction on assessing the hygrothermal performance of wall systems that included this innovative vapour retarder (Note: Vapour Barrier in Canadian terminology is equivalent to Vapor retarder in US terminology). The performance of walls was assessed when subjected to eastern coastal climate conditions of Halifax, one of the four Canadian climatic locations used in this study. A wood-framed stucco clad wall was the reference assembly. Results from different cases based on the variation of vapour control strategies and their effect on the hygrothermal performance of the wall systems are analysed. The results for the Halifax climate location indicate that the installation of a humidity controlled, innovative vapour retarder is a recommendable solution for the envelope design of residential buildings of these locations with moderate or high water vapour permeance of the interior paint. In this study, the advanced hygrothermal tool, hygIRC, was used to perform the hygrothermal performance analysis of the wall systems., Peer reviewed article, Published. A version of this document is published in: 4th International Building Physics Conference, Istanbul, Turkey, June 15-18, 2009, pp. 1-8.
Hygrothermal performance of RH-dependent vapour retarder in Canadian coastal climate
Proceedings of 12th Canadian Conference of Building Science and Technology: 06 May 2009, Montreal, QC. The hygrothermal performance of wood-frame wall with stucco cladding exposed to the coastal climate of Vancouver, BC, is studied. The primary objective of the study is to compare the moisture management performance of two vapour barriers: the relatively new SmartVapour Retarder (SVR) and commonly used Polyethylene sheet. For a reference purpose a wood-frame wall with no vapour barrier is considered as well. The performances of these three walls, which are exposed to the same indoor and outdoor climatic loads, are compared with respect to their dynamic responses to two simulation variables: interior moisture load (simulated water intrusion in the stud cavity) and paint on the interior gypsum board. The water intrusion is assumed to be through defect areas and the quantity is correlated with the amount of wind-driven rain that the wall is exposed to. The hygrothermal simulation results suggest that adoption of SVR as a vapour barrier yields better moisture management of the sheathing board (OSB) for any conditions considered in this paper including internal moisture load and interior paint. But, in coastal climate, it may have adverse effect on the moisture management of the interior gypsum board, in cases where water leaks into the cavity and the interior gypsum board is painted with low-vapour permeance paint., Peer reviewed article, Published. A version of this document is published in: 12th Canadian Conference of Building Science and Technology, Montreal, QC, May 6-8, 2009, pp. 1-12
Hygrothermal performance of ventilated attic in marine climate under different ceiling air tightness
14th International Conference on Indoor Air Quality and Climate (Indoor Air 2016), July 3-8, 2016, Ghent, Belgium. An indoor to attic air leakage and vice-versa significantly affect indoor air, thermal comfort and the hygrothermal performance in both living space and unconditioned space. In cold and marine climates an air leakage from living space to an attic brings a relatively high relative humidity to the attic space. This effect is primarily responsible for condensation in attic structural parts such as roof sheathings. In this paper, the hygrothermal performance of a ventilated attic in wet costal climates under different ceiling air leakage is studied. A benchmarked whole building Heat-Air-Moisture model named HAMFit is used to study hygrothermal performance of ventilated attics in marine climates. The attic is modelled as 2-dimensional geometry with coupled heat transfer, moisture transport and a turbulence Computational Fluid Dynamics through attic space and porous structural parts of the attic. A vent ratio of 1/300 and three types normalized leakage area (tight, normal and leaky) are used to analyse how the moisture transport behaves in ventilated space. A winter weather data of city of Vancouver, BC is used to represent a wet marine climate. Our findings show specific locations in the attic structure are more exposed to moisture related problems and the air circulation and temperature distribution due to ventilation under multiple ceiling air leakage scenarios are presented. Hygrothermal performance of ventilated attic in marine climate under different ceiling air tightness., Conference paper, Published.
Hygrothermal properties of exterior claddings, sheathing boards, membranes and insulation materials for building envelope design
Proceedings of Thermal Performance of the Exterior Envelopes of Whole Buildings X International Conference: 02 December 2007, Clearwater, Florida. Testing was conducted to determine those construction material properties that affect the movement of heat, air, and moisture in building envelopes. The paper reports the density, thermal conductivity, equilibrium moisture content, water vapor permeability, water absorption coefficient, liquid diffusivity, and air permeability of twenty-three building materials commonly used in North American including: exterior claddings, exterior sheathing boards, membranes and insulations. The paper also discusses the experimental and analytical procedures used to determine these properties., Conference paper, Published. A version of this document is published in: Proceedings of Thermal Performance of the Exterior Envelopes of Whole Buildings X, Clearwater, Florida, Dec. 2-7, 2007, pp. 1-16.
Identification of quantitative trait loci controlling fibre length and lignin content in Arabidopsis thaliana stems
Fibre properties and the biochemical composition of cell walls are important traits in many applications. For example, the lengths of fibres define the strength and quality of paper, and lignin content is a critical parameter for the use of biomass in biofuel production. Identifying genes controlling these traits is comparatively difficult in woody species, because of long generation times and limited amenability to high-resolution genetic mapping. To address this problem, this study mapped quantitative trait loci (QTLs) defining fibre length and lignin content in the Arabidopsis recombinant inbred line population Col-4×Ler-0. Adapting high-throughput phenotyping techniques for both traits for measurements in Arabidopsis inflorescence stems identified significant QTLs for fibre length on chromosomes 2 and 5, as well as one significant QTL affecting lignin content on chromosome 2. For fibre length, total variation within the population was 208% higher than between parental lines and the identified QTLs explained 50.58% of the observed variation. For lignin content, the values were 261 and 26.51%, respectively. Bioinformatics analysis of the associated intervals identified a number of candidate genes for fibre length and lignin content. This study demonstrates that molecular mapping of QTLs pertaining to wood and fibre properties is possible in Arabidopsis, which substantially broadens the use of Arabidopsis as a model species for the functional characterization of plant genes., Peer-reviewed article, Published. Received 3 April 2012; Revised 11 October 2012; Accepted 15 October 2012.
Impact of electrical intertie capacity on carbon policy effectiveness
This study investigates the potential cost and emissions reductions that result from an increase in electricity transmission capacity between Canada's two westernmost provinces: Alberta, a fossil fuel dominated jurisdiction, and British Columbia, a predominantly hydroelectric jurisdiction. A bottom-up model is used to find the least cost electricity generation mix in Alberta and British Columbia under different carbon policies. The long-term evolution of the electricity system is determined by minimizing net present cost of electricity generation for the time span of 2010–2060. Different levels of intertie capacity expansion are considered together with a variety of carbon tax and carbon cap scenarios. Results indicate that increased intertie capacity reduces the cost of electricity and emissions under carbon pricing policies. However, the expandable intertie does not encourage greater adoption of variable renewable generation. Instead, it is used to move low-cost energy from the United States to Alberta. The optimal intertie capacity and cost reduction of increased interconnectivity increases with more restrictive carbon policies., Peer-reviewed article, Published. Received 3 March 2016, Revised 23 September 2016, Accepted 12 October 2016, Available online 15 November 2016.
The impact of spinal cord injury on sexual function
Study Design: Secure, web-based survey. Objectives: Obtain information from the spinal cord injured (SCI) population regarding sexual dysfunctions, with the aim of developing new basic science and clinical research and eventual therapies targeting these issues. Setting: Worldwide web. Methods: Individuals 18 years or older living with SCI. Participants obtained a pass-code to enter a secure website and answered survey questions. A total of 286 subjects completed the survey. Results: The majority of participants stated that their SCI altered their sexual sense of self and that improving their sexual function would improve their quality of life (QoL). The primary reason for pursuing sexual activity was for intimacy need, not fertility. Bladder and bowel concerns during sexual activity were not strong enough to deter the majority of the population from engaging in sexual activity. However, in the subset of individuals concerned about bladder and/or bowel incontinence during sexual activity, this was a highly significant issue. In addition, the occurrence of autonomic dysreflexia (AD) during typical bladder or bowel care was a significant variable predicting the occurrence and distress of AD during sexual activity. Conclusion: Sexual function and its resultant impact on QoL is a major issue to an overwhelming majority of people living with SCI. This certainly constitutes the need for expanding research in multiple aspects to develop future therapeutic interventions for sexual health and SCI., Peer-reviewed article, Published.
Impact of V2G on real-time adaptive Volt/VAr optimization of distribution networks
Proceeding of IEEE ElectricalPower and Energy Conference (EPEC 2013), Aug. 2013, Halifax, Canada. Deployment of Smartgrid downstream features such as Smart Metering, pervasive control and Distributed Management Systems has brought great opportunities for distribution network planners to optimize the network in more precise methods. Moreover, the advent of Electric Vehicles (EVs) has brought more opportunities for grid optimization. Recent studies stipulate that EVs are able to inject reactive power into the grid by changing their inverter's operating mode. This paper primarily discusses a real-time adaptive Volt/VAr Optimization (VVO) engine, designed to minimize system apparent power losses, optimize voltage profiles, and reduce the operating costs of Switched Capacitor Banks of the grid. The paper goes on to study the impact of EVs on the distribution network VVO, taking into account different EV charging and penetration levels and checks the validity of the proposed algorithm by employing revised IEEE-37 Node Test Feeder in presence of various load types as a case study., Conference paper, Published.

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