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BCIT Citations Collection

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Development and evaluation of a compliance-independent pressure transducer for biomedical applications
Proceedings of 17th International Conference of the Engineering in Medicine and Biology Society, Montreal, Quebec, Canada, on 20-23 Sept. 1995. The measurement of pressure at a device/tissue interface is desirable in many biomedical engineering applications such as tourniquets and mammography in order to optimize the design or performance of the device. Testing of a selection of existing interface transducers has demonstrated that many are dependent on device and tissue compliance. Such a transducer is only useful in an application where it has been calibrated for specific device/tissue compliance combinations. To overcome this limitation the authors have developed an interface pressure transducer whose output signal is not affected by changes in interface compliance. This enables the transducer to quantitatively measure pressure in many applications without the need to calibrate the transducer for varying compliance conditions. The signal from such a transducer could be incorporated into a control system to measure and control the pressure applied by a mammography machine to the breast., Conference paper, Published.
Development and evaluation of an interface pressure transducer for biomedical applications
The measurement of the interface pressure between a biomedical device and part of the human body is useful to aid in the design or improve the performance and safety of such devices. Therefore, a need exists for a transducer to measure interface pressure in these applications. The development and evaluation of an interface pressure transducer was the main goal of this research. Surgical retraction, surgical tourniquets and mammography were selected as demonstration applications for the developed transducer. These target applications were selected because they represented a wide spectrum of device and tissue characteristics and properties, and were in common use. A review of the available clinical, commercial and engineering literature identified a wide range of transducers and transducer technologies used for interface pressure measurement. The transducers included pneumatic/hydraulic, fibre-optic, strain based, capacitive and micromachined technologies. No standard method of measuring interface pressure was described and, in many cases, investigators cautioned against comparing-interface pressure measurements obtained using different measurement systems. From this review and an examination of the biomedical applications mentioned, the design criteria and optimal design specifications for an interface pressure transducer were defined. To gain a better understanding of the mechanical response of the interface between a device, transducer, and tissue to an applied loading, a preliminary finite element model was developed and studied. The model demonstrated the potential for shear stresses to develop between the transducer and interface materials. Furthermore a calibration system which simulated interface conditions was developed to evaluate both existing and developed transducers for use as interface pressure transducers. This evaluation demonstrated the lack of a transducer whose output was independent of the compliance of the interface materials. As well, an essential characteristic was identified for an effective interface pressure transducer that could be used in several applications where the interface material compliance was different. Based on the knowledge gained from the finite element analysis and existing transducer evaluation results, a novel interface pressure transducer was developed and evaluated both in the calibration system and via demonstration applications of surgical retraction and tourniquets. Under laboratory conditions in the calibration system, the transducer met many of the desired design specifications. The transducer was tested in the lab under both pneumatic and nonpneumatic tourniquet cuffs. The transducer worked well under the pneumatic cuff but required ] further development for use under the non-pneumatic cuff. The transducer was also integrated into a surgical retractor and evaluated in five clinical trials. It met many of the desired specifications for this application., Thesis, Published.
Development and pilot testing of a kneeling ultralight wheelchair design
Proceedings of 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Milan, Italy, Aug 25-29 2015. "Dynamic wheeled mobility" offers "on the fly" seating adjustments for wheelchair users such that various activities performed throughout the day can be matched by an appropriate seat position. While this has benefits for user participation and health, the added weight in existing dynamic wheelchairs may impact the user's ability to transport the frame, e.g. into cars. Other dynamic features to enable more participation avenues are also desirable. This paper outlines the development of a "kneeling" ultralight wheelchair design that offers dynamic wheeled mobility functionality at a weight that is comparable to many existing ultralight wheelchairs. In addition, the wheelchair's kneeling function allows a lowered seat position to facilitate low-to-the-ground tasks such as floor transfers and other activities where sustained low level reaching may be required (e.g. playing with children, changing a tire, etc.). This paper also describes the development and pilot testing of an end user evaluation protocol designed to validate the wheelchair's functionality and performance. Successful realization and commercialization of the technology would offer a novel product choice for people with mobility disabilities, and that may support daily activities, health, improved quality of life, and greater participation in the community., Conference paper, Published.
Development of a micromachined pressure transducer for biomedical device/tissue interfaces
Proceedings of 1996 Canadian Conference on Electrical and Computer Engineering, Calgary, Alberta on 26-29 May 1996. In many medical situations, the need for measuring the pressure applied to a tissue quickly and accurately is crucial. Most conventional devices do not measure the actual pressure applied to the tissue because they do not compensate for the tissue or device compliance characteristics and need to be calibrated for each measurement environment. Neuromuscular damage may occur if too much pressure is applied to a tissue for an extended period of time in applications such as tourniquet systems. Incorrect diagnosis may occur if too little pressure is applied in applications such as mammography units. A compliance-independent pressure transducer has other biomedical applications in surgical retraction devices and prosthetic sockets. To eliminate the compliance problem, a pressure transducer was developed using bulk micromachining technology., Conference paper, Published.
The development of an ultralight wheelchair with dynamic seating
Proceedings of the Rehabilitation Engineering and Assistive Technology Society of North America Annual Conference 2011. The Elevation™ wheelchair was recently developed and introduced to the market as an alternative to conventional ultralight rigid wheelchairs normally used by paraplegics and others with disabilities necessitating the daily use of a manual wheelchair. The Elevation wheelchair provides independent user-adjustable seat positioning during normal usage. Elevation allows the user to quickly and easily adjust in real-time the seat height, as well as backrest recline angle, all in a manual ultralight rigid wheelchair form factor. This allows for dynamic seat positioning to suit the tasks and comfort of users throughout their daily activities. The rationale for and user-driven development of the Elevation wheelchair is summarized here., Conference paper, Published.
The dogs of war
This paper presents a two stage model of negligence and legal action. In the first stage the defendant decides on the level of due care to take while carrying out an action or activity. In the second stage an accident has occurred and the plaintiff brings suit. Lawyers (agents) invest in actions that are designed to increase the probability of success on behalf of their respective clients. First we present the symmetric casewhere all decisions on investment in legal services occur ex-post (after an accident has occured). We then look as the case where the potential injurer pre-commits to a level of legal services ex-ante (prior to an accident) and analyze the effect that pre-commitment in legal services has on the stage one choice of care. We then present a case study from the field of labour relations where strategic pre-commitment is used to influence the settlement of grievances. The grievance process in labour relations parallel civil litigation and a grievance can be viewed as equivalent to either a tort or a breach of contract; depending on the type of grievance., Essay, Published.
Dual organizational structures in franchising
This paper extends the work of Mathewson and Winter (1985) in the field of franchising. Given the hypothesis that a franchise contract ensures quality compliance at a lower cost relative to alternative organizational structures, the existence of dual organizational structures within the same franchise chain is inadequately explained. This paper extends the basic model of Mathewson and Winter into a spatial framework, demonstrating that nonconvexities in monitoring costs will produce dual organizational structures within the same chain., Essay, Published.
Dynamic plan management in the context of a recognized air picture
This document surveys existing literature on dynamic plan management and describes the development of a prototype Air Force plan management system. The literature survey presents short summaries of a wide range of research papers, as well as a synthesis and analysis of existing approaches. The detailed comparison of existing approaches is used to formulate a specific methodology for the development of software for plan representation, plan forecasting/projection, plan analysis/evaluation and plan monitoring. The proposed methodology involves the development of a precise ontology of plan elements for plan representation. This representation removes ambiguity in the description of plans, facilitates automated analysis of plans, and also permits several different approaches to plan visualization. The implemented prototype software defines an ontology that provides a suitable internal representation of plans, along with basic plan validation capabilities. It also provides a map-based graphical user interface to visualize plans. The use of the software is demonstrated in the context of a combat search and rescue vignette. The findings conclude that the prototype demonstrates the overall utility of the approach, although further development is required to provide more detailed analysis, as well as additional visualization methods., Research report, Published.
Dynamic wheeled mobility
31st International Seating Symposium, Nashville, TN, February 26-28, 2015. The prevalence of upper limb pain in full-time manual wheelchair users living with SCI is estimated to be anywhere from 30-70%. For those who rely on an ultralight wheelchair for their day-to-day function, the consequences can be significant and will impact more than just their mobility. Since they were published in 2005, the Clinical Practice Guidelines for Preservation of Upper Limb Function Following Spinal Cord Injury (CPG’s) have served as a valuable evidence-based resource for clinicians and seating/wheeled mobility professionals who work with the SCI population. The recommendations related to wheelchair use are based on extensive research that has examined the effects of the wheelchair’s configuration and the user’s propulsion technique on upper limb function. The recommendations focus on three general areas: Ergonomics, Equipment Selection, and Training., Conference paper, Published.
Early developmental activities and computing proficiency
Proceedings from the 2017 ITiCSE Conference on Working Group Reports. As countries adopt computing education for all pupils from primary school upwards, there are challenging indicators: significant proportions of students who choose to study computing at universities fail the introductory courses, and the evidence for links between formal education outcomes and success in CS is limited. Yet, as we know, some students succeed without prior computing experience. Why is this? Some argue for an innate ability, some for motivation, some for the discrepancies between the expectations of instructors and students, and some -- simply -- for how programming is being taught. All agree that becoming proficient in computing is not easy. Our research takes a novel view on the problem and argues that some of that success is influenced by early childhood experiences outside formal education. In this study, we analyzed over 1300 responses to a multi-institutional and multi-national survey that we developed. The survey captures enjoyment of early developmental activities such as childhood toys, games and pastimes between the ages 0 --- 8 as well as later life experiences with computing. We identify unifying features of the computing experiences in later life, and attempt to link these computing experiences to the childhood activities. The analysis indicates that computing proficiency should be seen from multiple viewpoints, including both skill-level and confidence. Our analysis is the first to show, we believe, that particular early childhood experiences are linked to parts of computing proficiency, namely those related to confidence with problem solving using computing technology. These are essential building blocks for more complex use. We recognize issues in the experimental design that may prevent our data showing a link between early activities and more complex computing skills, and suggest adjustments for future studies. Ultimately, we expect that this line of research will feed in to early years and primary education, and thereby improve computing education for all., Peer reviewed, Conference paper, Published.
EE13-2 development and benchmarking of a new whole building hygrothermal model
Proceedings of Building Enclosure Science & Technology (BEST2) Conference, Portland, USA, April 12-14, 2010. During design process, building engineers evaluate the performance of various design alternatives in terms of their durability, comfort and indoor air quality, as well as energy efficiency using building envelope, indoor and energy analysis tools, respectively. But, usually the analysis tools are in the form of stand-alone package, where there is no direct link among them but rather simplifying assumptions are made on the other two when designing for one. In this paper, the development and benchmarking of a newly developed whole building hygrothermal model are presented. The model considers the building as a system and accounts for the dynamic heat, air and moisture (HAM) interaction between building envelope components and indoor environmental conditions including HVAC systems, moisture and heat sources. The methodology adopted in this work is to develop and validate two primary models: building envelope and indoor models independently and couple them to form the whole building hygrothermal model. After successful integration of the models, the whole building hygrothermal model is benchmarked against internationally published numerical and experimental test results. The holistic model can be used to assess building enclosures durability, indoor conditions (temperature and relative humidity), occupant comfort, and energy efficiency of a building in an integrated manner., Conference paper, Published.
The effects of gene recruitment on the evolvability and robustness of pattern-forming gene networks
Gene recruitment or co-option is defined as the placement of a new gene under a foreign regulatory system. Such re-arrangement of pre-existing regulatory networks can lead to an increase in genomic complexity. This reorganization is recognized as a major driving force in evolution. We simulated the evolution of gene networks by means of the Genetic Algorithms (GA) technique. We used standard GA methods of point mutation and multi-point crossover, as well as our own operators for introducing or withdrawing new genes on the network. The starting point for our computer evolutionary experiments was a 4-gene dynamic model representing the real genetic network controlling segmentation in the fruit fly Drosophila. Model output was fit to experimentally observed gene expression patterns in the early fly embryo. We compared this to output for networks with more and less genes, and with variation in maternal regulatory input. We found that the mutation operator, together with the gene introduction procedure, was sufficient for recruiting new genes into pre-existing networks. Reinforcement of the evolutionary search by crossover operators facilitates this recruitment, but is not necessary. Gene recruitment causes outgrowth of an evolving network, resulting in redundancy, in the sense that the number of genes goes up, as well as the regulatory interactions on the original genes. The recruited genes can have uniform or patterned expressions, many of which recapitulate gene patterns seen in flies, including genes which are not explicitly put in our model. Recruitment of new genes can affect the evolvability of networks (in general, their ability to produce the variation to facilitate adaptive evolution). We see this in particular with a 2-gene subnetwork. To study robustness, we have subjected the networks to experimental levels of variability in maternal regulatory patterns. The majority of networks are not robust to these perturbations. However, a significant subset of the networks do display very high robustness. Within these networks, we find a variety of outcomes, with independent control of different gene expression boundaries. Increase in the number and connectivity of genes (redundancy) does not appear to correlate with robustness. Indeed, removal of recruited genes tends to give a worse fit to data than the original network; new genes are not freely disposable once they acquire functions in the network., Book chapter, Published.

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